Impact of edge-removal on the centrality betweenness of the best spreaders

The control of epidemic spreading is essential to avoid potential fatal consequences and also, to lessen unforeseen socio-economic impact. The need for effective control is exemplified during the severe acute respiratory syndrome (SARS) in 2003, which has inflicted near to a thousand deaths as well as bankruptcies of airlines and related businesses. In this article, we examine the efficacy of control strategies on the propagation of infectious diseases based on removing connections within real world airline network with the associated economic and social costs taken into account through defining appropriate quantitative measures. We uncover the surprising results that removing less busy connections can be far more effective in hindering the spread of the disease than removing the more popular connections. Since disconnecting the less popular routes tend to incur less socio-economic cost, our finding suggests the possibility of trading minimal reduction in connectivity of an important hub with efficiencies in epidemic control. In particular, we demonstrate the performance of various local epidemic control strategies, and show how our approach can predict their cost effectiveness through the spreading control characteristics.Comment: 11 pages, 4 figure

New Production Mechanism of Neutral Higgs Bosons with Right scalar tau neutrino as the LSP

Motived by the neutrino oscillation data, we consider the lightest tau sneutrino $\tilde \nu_{\tau_1}$ (which is mostly the right tau sneutrino) to be the lightest supersymmetric particle (LSP) in the framework of the minimal supersymmetric Standard Model. Both the standard and the non-standard trilinear scalar coupling terms are included for the right tau sneutrino interactions. The decay branching ratio of $\tilde \nu_{\tau_2} \to \tilde \nu_{\tau_1}+ h^0$ can become so large that the production rate of the lightest neutral Higgs boson ($h^0$) can be largely enhanced at electron or hadron colliders, either from the direct production of $\tilde \nu_{\tau_2}$ or from the decay of charginos, neutralinos, sleptons, and the cascade decay of squarks and gluinos, etc. Furthermore, because of the small LSP annihilation rate, $\tilde \nu_{\tau_1}$ can be a good candidate for cold dark matter.Comment: 11 pages, RevTex, 3 eps figures. We clarify the theoretical framework of this study, with a note added in the end, and correct an equation, with updated figure

Multivariate Fitting and the Error Matrix in Global Analysis of Data

When a large body of data from diverse experiments is analyzed using a theoretical model with many parameters, the standard error matrix method and the general tools for evaluating errors may become inadequate. We present an iterative method that significantly improves the reliability of the error matrix calculation. To obtain even better estimates of the uncertainties on predictions of physical observables, we also present a Lagrange multiplier method that explores the entire parameter space and avoids the linear approximations assumed in conventional error propagation calculations. These methods are illustrated by an example from the global analysis of parton distribution functions.Comment: 13 pages, 5 figures, Latex; minor clarifications, fortran program made available; Normalization of Hessian matrix changed to HEP standar

Experimental demonstration of an efficient quantum phase-covariant cloning and its possible applications to simulating eavesdropping in quantum cryptography

We describe a nuclear magnetic resonance (NMR) experiment which implements an efficient one-to-two qubit phase-covariant cloning machine(QPCCM). In the experiment we have achieved remarkably high fidelities of cloning, 0.848 and 0.844 respectively for the original and the blank qubit. This experimental value is close to the optimal theoretical value of 0.854. We have also demonstrated how to use our phase-covariant cloning machine for quantum simulations of bit by bit eavesdropping in the four-state quantum key distribution protocol.Comment: 4 pages, 5 figure

Analyzing powers in inclusive pion production at high energy and the nucleon spin structure

Analyzing powers in inclusive pion production in high energy transversely polarized proton-proton collisions are studied theoretically in the framework of the quark recombination model. Calculations by assuming the SU(6) spin-flavor symmetry for the nucleon structure disagree with the experiments. We solve this difficulty by taking into account the %We overcome this difficulty by taking into account the realistic spin distribution functions of the nucleon, which differs from the SU(6) expectation at large $x$, %but coincides with a perturbative QCD constraint on the ratio of the unpolarized valence distributions, $u/d \to 5$ as $x \to 1$. We also discuss the kaon spin asymmetry and find $A_N(K^+) = -A_N(K^0)$ in the polarized proton-proton collisions at large $x_F$.Comment: 13 pages, 4 figures, late

Black Hole Production by Cosmic Rays

Ultra-high energy cosmic rays create black holes in scenarios with extra dimensions and TeV-scale gravity. In particular, cosmic neutrinos will produce black holes deep in the atmosphere, initiating quasi-horizontal showers far above the standard model rate. At the Auger Observatory, hundreds of black hole events may be observed, providing evidence for extra dimensions and the first opportunity for experimental study of microscopic black holes. If no black holes are found, the fundamental Planck scale must be above 2 TeV for any number of extra dimensions.Comment: 4 pages, 4 figures, PRL versio

Cyclosporine augments hepatic regenerative response in rats

A number of mechanisms participate in the hepatic injury that occurs during and following liver transplantation. A normal allograft regenerative response is probably essential for a successful transplant outcome. In this study, the effect of cyclosporine, a potent immunosuppressant used routinely after liver transplantation, on the regenerative response of the liver after partial hepatectomy was investigated. Male Wistar rats were pretreated for one week with either cyclosporine or the olive oil vehicle and were subjected to either a two-thirds partial hepatectomy or a sham operation. Animals were sacrificed at various times postoperatively and the remnant livers were weighed to determine the liver weight to body weight ratio, two biochemical measures of a regenerative response (cytosolic ornithine decarboxylase activity and thymidine kinase activity), and the hepatic content of estrogen and androgen receptors, as the content of these receptors has been shown to modulate, at least in part, the subsequent hepatic regenerative response. The preoperative hepatic cytosol content of ornithine decarboxylase, thymidine kinase, and estrogen receptor was significantly greater (P<0.05) in rats pretreated with cyclosporine than in those treated with the vehicle alone. A significant increase in ornithine decarboxylase and thymidine kinase activities occurred after partial hepatectomy in both the cyclosporine-pretreated and vehicle-pretreated animals. The absolute levels for each parameter were also greater in the cyclosporine-treated animals than in the vehicle-treated controls at 24 hr after partial hepatectomy (P<0.05). The pattern of change in the hepatic cytosolic content of estrogen and androgen receptors in both groups of animals was comparable with those described previously for regenerating liver. These data suggest that cyclosporine may predispose the liver to respond to either a regenerative signal or perceived need and thereby fortuitously enhance liver graft performance after successful surgical implantation. © 1989 Plenum Publishing Corporation